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Off-label use for hyperbilirubinemia: Phenobarbital induces glucuronyl transferase and hepatic bilirubin-binding Y-protein to reduced serum bilirubin concentrationsMonitor Carefully (one)somatropin will lower the extent or impact of phenobarbital by influencing hepatic/intestinal enzyme CYP3A4 metabolism.In reports, secobarbital sodium and pentobar